Dal 2013 svolgo attività di ricerca nell’ambito dell’invecchiamento e delle patologie correlate, con particolare interesse ai temi della prevenzione della demenza, della diagnosi precoce, delle terapie non-farmacologiche e dell’invecchiamento attivo.

Mi appassiona e incuriosisce approfondire come le caratteristiche e il comportamento delle persone possano contribuire a mitigare gli effetti delle malattie neurodegenerative, affinché queste informazioni possano aiutare a migliore e preservare la qualità della vita durante l’invecchiamento.

Aree di ricerca
e relative pubblicazioni

COVID-19 e benessere psicosociale della popolazione anziana

Rolandi E, Vaccaro R, Abbondanza S, Casanova G, Pettinato L, Colombo M, Guaita A, 2020. Loneliness and Social Engagement in Older Adults Based in Lombardy during the COVID-19 Lockdown: The Long-Term Effects of a Course on Social Networking Sites Use. Int J Environ Res Public Health. 17(21):7912. doi:10.3390/ijerph17217912

Carlos AF, Poloni TE, Caridi M, Pozzolini M, Vaccaro R, Rolandi E, Cirrincione A, Pettinato L, Vitali SF, Tronconi L, Ceroni M, Guaita A. Life during COVID-19 lockdown in Italy: the influence of cognitive state on psychosocial, behavioral and lifestyle profiles of older adults. Aging Ment Health. 2021 Jan 15:1-10. doi: 10.1080/13607863.2020.1870210.

Senior e nuove tecnologie

Casanova G, Zaccaria D, Rolandi E, Guaita A. The Effect of Information and Communication Technology and Social Networking Site Use on Older People’s Well-Being in Relation to Loneliness: Review of Experimental Studies. J Med Internet Res. 2021 Mar 1;23(3):e23588. doi: 10.2196/23588.

Zaccaria D, Guaita A, Vaccaro R, Casanova G, Abbondanza S, Pettinato L, Cerati G, Rolandi E, Sala E, 2020. Assessing the impact of Social Networking Site use on older people’s loneliness and social isolation. A randomized controlled trial: The Aging in a Networked Society-Social Experiment Study (ANS-SE). Contemp Clin Trials Commun;19(March):100615. doi:10.1016/j.conctc.2020.100615

Vaccaro R, Colombo M, Abbondanza S, Rolandi E, Pettinato L, Guaita A, 2020. Technology Usage among Elderly with Self-Reported Hearing Disability: Results from InveCe.Ab. Health (Irvine Calif);12(04):353-367. doi:10.4236/health.2020.124029

Demenza: fattori di rischio e prevenzione

Rolandi E, Zaccaria D, Vaccaro R, Abbondanza S, Pettinato L, Davin A, Guaita A. 2020. Estimating the potential for dementia prevention through modifiable risk factors elimination in the real-world setting: A population-based study. Alzheimer’s Res Ther;12(1). doi:10.1186/s13195-020-00661-y

Rolandi E, Dodich A, Galluzzi S, Ferrari C, Mandelli S, Ribaldi F, Munaretto G, Ambrosi C, Gasparotti R, Violi D, Canessa N, Iannaccone S, Marcone A, Falini A, Hampel H, Frisoni GB, Cerami C, Cavedo E, 2019. Randomized controlled trial on the efficacy of a multilevel non-pharmacologic intervention in older adults with subjective memory decline: design and baseline findings of the E.Mu.N.I. study. Aging Clin Exp Res. doi:10.1007/s40520-019-01403-3

Rolandi E, Cavedo E, Pievani M, Galluzzi S, Ribaldi F, Buckley C, Cunningham C, Guerra UP, Musarra M, Morzenti S, Magnaldi S, Patassini M, Terragnoli F, Matascioli L, Franzoni S, Annoni G, Carnevali L, Bellelli G, Frisoni GB, 2017. Association of postoperative delirium with markers of neurodegeneration and brain amyloidosis. A pilot study. Neurobiol. Aging. 61, 93-101. http://dx.doi.org/10.1016/j.neurobiolaging.2017.09.020

Rolandi E, Frisoni, GB, Cavedo, E, 2016. Efficacy of lifestyle interventions on clinical and neuroimaging outcomes in elderly. Ageing Res. Rev. 25, 1–12. doi:10.1016/j.arr.2015.11.003

Diagnosi precoce della Malattia di Alzheimer

Marizzoni M, Ferrari C, Babiloni C, Albani D, Barkhof F, Cavaliere L, Didic M, Forloni G, Fusco F, Galluzzi S, Hensch T, Jovicich J, Marra C, Molinuevo JL, Nobili F, Parnetti L, Payoux P, Ranjeva JP, Ribaldi F, Rolandi E, Rossini PM, Salvatore M, Soricelli A, Tsolaki M, Visser PJ, Wiltfang J, Richardson JC, Bordet R, Blin O, Frisoni GB, 2020. CSF cutoffs for MCI due to AD depend on APOEε4 carrier status. Neurobiol Aging;89:55-62. doi:10.1016/j.neurobiolaging.2019.12.019

Nathan, P.J., Lim, Y.Y., Abbott, R., Galluzzi, S., Marizzoni, M., Babiloni, C., Albani, D., Bartres-Faz, D., Didic, M., Farotti, L., Parnetti, L., Salvadori, N., Müller, B.W., Forloni, G., Girtler, N., Hensch, T., Jovicich, J., Leeuwis, A., Marra, C., Molinuevo, J.L., Nobili, F., Pariente, J., Payoux, P., Ranjeva, J.-P., Rolandi, E., Rossini, P.M., Schönknecht, P., Soricelli, A., Tsolaki, M., Visser, P.J., Wiltfang, J., Richardson, J.C., Bordet, R., Blin, O., Frisoni, G.B., PharmaCog Consortium, 2017. Association between CSF biomarkers, hippocampal volume and cognitive function in patients with amnestic mild cognitive impairment (MCI). Neurobiol. Aging 53, 1–10. doi:10.1016/j.neurobiolaging.2017.01.013

Galluzzi, S., Marizzoni, M., Babiloni, C., Albani, D., Antelmi, L., Bagnoli, C., Bartres-Faz, D., Cordone, S., Didic, M., Farotti, L., Fiedler, U., Forloni, G., Girtler, N., Hensch, T., Jovicich, J., Leeuwis, A., Marra, C., Molinuevo, J.L., Nobili, F., Pariente, J., Parnetti, L., Payoux, P., Del Percio, C., Ranjeva, JP., Rolandi, E., Rossini, P.M., Schönknecht, P., Soricelli, A., Tsolaki, M., Visser, P.J., Wiltfang, J., Richardson, J.C., Bordet, R., Blin, O., Frisoni, G.B., PharmaCog Consortium, 2016. Clinical and biomarker profiling of prodromal Alzheimer’s disease in workpackage 5 of the Innovative Medicines Initiative PharmaCog project: a “European ADNI study”. J. Intern. Med. 279, 576–91. doi:10.1111/joim.12482

Plasticità cerebrale

Gandola, M., Bruno, M., Zapparoli, L., Saetta, G., Rolandi, E., De Santis, A., Banfi, G., Zerbi, A., Sansone, V., Paulesu, E., 2017. Functional brain effects of hand disuse in patients with trapeziometacarpal joint osteoarthritis: executed and imagined movements. Exp. Brain Res. 1–15. doi:10.1007/s00221-017-5049-6